Severe Asthma characterization in phenotypes and endotypes, by means of specific biomarkers, have led to the dichotomization of the concepts of 'personalized medicine' and 'precision medicine', which are often used as synonyms, but actually have slight meaning differences in meaning.
Personalized–precision medicine would bring to better treatment strategies in dealing with severe asthmatic patients.
In effect, the introduction of biologic therapies, which are specific therapies, has necessitated the introduction of some aspects of personalized medicine in the use of biomarkers to define clinical phenotypes that respond to such precisely targeted treatments, mainly focused on treatable traits
